I make my "Renaissance 3D" visuals in 3D Modo and Octane.
I keep post-production to a minimum; depending on the situation, I solve everything in 3D and let it render...
When that's done, only a slight tweak in Lightroom or Photoshop make it perfect.
Below: large and highly detailed "Renaissance 3d" photorealistic visuals. (The linked images are up to 1 Mb in size!)